Effect of dicamba and its active ingredient, 
dicamba (3,6-dichloro-o-anisic acid) was investigated employing rabbit mucus 
membrane irritancy test. Inflammatory changes which did not exceed an average 
score of 2+ were observed in the animals 48 hr after a single intravaginal 
application of dicamba (0.1 ml/rabbit) and dicamba (100 mg/rabbit). 
Persistent histopathological changes were observed in 1 out of 6 banvel-treated 
rabbits 15 days post-application. The results suggest that banvel and dicamba are not primary irritants but should nevertheless be 
employed with caution
Yangzhou pioneer chemical CO.,LTD.
 
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