Dicamba is actually an old herbicide that served alongside “agent orange” in Vietnam [7], and has been resurrected as an environmentally friendly chemical through the magic of public relations.
Dicamba degradation was characterized in the bacterium Psuedomonas maltophilia , which can utilize the herbicide as a sole carbon source. Three separate enzymes, an oxygenase, a ferredoxin and a reductase act sequentially to convert Dicamba to its first degradation product 3,6-dichlorsalyicylic acid [8].The primary patent for Dicamba degrading organisms including transgenic crops was assigned to the University of Nebraska. The genes for the Dicamba oxygenase, ferridoxin and reductase were used to transform crop plants. No selectable markers were required because the transformants could be identified by the fluorescence of 3,6-dichlorsalyicylic acid [9].
Dicamba degradation was characterized in the bacterium Psuedomonas maltophilia , which can utilize the herbicide as a sole carbon source. Three separate enzymes, an oxygenase, a ferredoxin and a reductase act sequentially to convert Dicamba to its first degradation product 3,6-dichlorsalyicylic acid [8].The primary patent for Dicamba degrading organisms including transgenic crops was assigned to the University of Nebraska. The genes for the Dicamba oxygenase, ferridoxin and reductase were used to transform crop plants. No selectable markers were required because the transformants could be identified by the fluorescence of 3,6-dichlorsalyicylic acid [9].
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