Zhang Zhenming,Jia Yonggang,Wang Canming,Gao Shan,Liang Min,Sun Ke (Shenyang Research Institute of Chemical Industry,Shenyang 110021,China)
Chlorobenzylamine was prepared by amination of p-chlorobenzylchloride with hexamethylenetetramine.A solution of 4-chlorobenzylamine and cyclopentyltanone were dissolved in ethanol,and were poured in the autoclave,and a mixture was condensed and hydrogenated to give N-4-chlorobenzyl-N-cycopentylamine on the catalyst at 3.5kg/cm 2 H at 40℃. Finally,a toluene solution of N-4-chlorobenzyl-N-cycopentylamine was treated with phenylisocyanate,and heated at 50℃ for 8h affored pencycuron with 95% purity. The total yield was 67.3% based on the starting material of p-chlorobenzylchlorde.
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